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Identification and ecotoxicity assessment of intermediates generated during the degradation of clofibric acid by advanced oxidation processes

Wenzhen LI, Yu DING, Qian SUI, Shuguang LU, Zhaofu QIU, Kuangfei LIN

Frontiers of Environmental Science & Engineering 2012, Volume 6, Issue 4,   Pages 445-454 doi: 10.1007/s11783-012-0419-6

Abstract: The acute toxicity was evaluated by means of T spp. bioassay.

Keywords： clofibric acid     advanced oxidation processes     intermediates     toxicity     Photobacterium phosphoreum T3 spp.    

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spp., foodborne pathogens threatening neonates and infants

Qiming CHEN, Yang ZHU, Zhen QIN, Yongjun QIU, Liming ZHAO

Frontiers of Agricultural Science and Engineering 2018, Volume 5, Issue 3,   Pages 330-339 doi: 10.15302/J-FASE-2018208

Abstract:

Cronobacter spp.Cronobacter spp. can resist dry environments and survive for a long period in food with low waterTherefore, Cronobacter spp. have become serious pathogens of neonates and infants, as well asreview, we present the taxonomy, pathogenesis, resistance, detection and control of Cronobacter spp.

Keywords： Cronobacter spp.    

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A CASE FOR ASSESSING ALLOCASUARINA AND CASUARINA SPP.

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4,   Pages 568-582 doi: 10.15302/J-FASE -2019270

Abstract:

Agroecosystems in water-limited contexts— Mediterranean, semi-arid and arid climatic zones—are too frequently degraded systems that will not provide the needed ecosystem services to ensure a future of sustainable agricultural production. The processes that have created this situation continue and are being accelerated by anthropogenic climate change. Increasing arboreal vegetation in these areas through agroforestry is an important strategy to conserve and improve their agroecosystems. Actinorhizal trees and shrubs in the Casurinaceae have a unique set of adaptations for heat and water stress, and/or infertile to hostile soils. Central Anatolia, Turkey is particularly at risk of increasing aridity and further degradation. Therefore, species of Allocasuarina and Casuarina have been evaluated for their potential use in agroecosystem improvement in semi-arid areas with a focus on Central Anatolia. Based on a semiquantitative environmental tolerance index and reported plant stature, eight species were identified as being of high (A. verticillata and C. pauper) to moderate (A. acutivalvis, A. decaisneana, A. dielsiana, A. huegeliana, C. cristata and C. obesa) priority for assessment, with none of these species having been adequately evaluated for agroforestry deployment in semi-arid agroecosystems in any context.

 

Keywords： actinorrhizal trees / agroforestry / climate change / ecosystem restoration    

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Repeats in the transcribed regions: comprehensive characterization and comparison of

Manosh Kumar BISWAS, Christoph MAYER, Xiuxin DENG

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 4,   Pages 421-432 doi: 10.15302/J-FASE-2017160

Abstract: A large number of expressed sequences tags are available for spp., which provides an opportunity toelements including tandem repeats (TRs) and transposable elements (TEs) in the transcribed region of the spp.

Keywords： Citrus spp.     tandem repeats     transcribed region     transposable elements    

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CRISPR-Cas9 mediated LAG-3 disruption in CAR-T cells

Yongping Zhang, Xingying Zhang, Chen Cheng, Wei Mu, Xiaojuan Liu, Na Li, Xiaofei Wei, Xiang Liu, Changqing Xia, Haoyi Wang

Frontiers of Medicine 2017, Volume 11, Issue 4,   Pages 554-562 doi: 10.1007/s11684-017-0543-6

Abstract:

T cells engineered with chimeric antigen receptor (CAR) have been successfully applied to treat advancedOne negative regulator of T cell activity is lymphocyte activation gene-3 (LAG-3).We successfully generated LAG-3 knockout T and CAR-T cells with high efficiency using LAG-3 knockout CAR-T cells displayed robust antigen-specific antitumor activity incell culture and in murine xenograft model, which is comparable to standard CAR-T cells.

Keywords： CAR-T     CRISPR-Cas9     LAG-3    

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Influence and related mechanism of Retn gene expression on glucose uptake in 3T3-L1 cells

LI Yahui, DONG Shiyuan, YU Chao, JIANG Yu, LI Huaixing, SUN Shuhan

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 269-273 doi: 10.1007/s11684-007-0051-1

Abstract: investigate the influence and the related mechanism of the gene on glucose uptake and insulin resistance in 3T3Radioimmunoassay was used to determine glucose uptake in 3T3-L1 cells with different gene expressionreal-time RT-PCR analysis were used to determine the mRNA levels of several glucose transport proteins in 3T3The glucose uptake decreased with the increase in gene expression in 3T3-L1 cells, which was independent, GSK-3 and p38MAPK, increased with overexpression in 3T3-L1 cells.

Keywords： 3T3-L1     influence     resistance     receptor substrate-1     transport    

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Novel mutation c.1210-3C>G in with a poly-T tract of 5T affects mRNA splicing in a Chinese patient

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 150-155 doi: 10.1007/s11684-021-0846-5

Abstract: The patient is a compound heterozygote of c.2909G>A, p.Gly970Asp in exon 18 and c.1210-3C>G in cis with a poly-T of 5T (T5) sequence, 3 bp upstream in intron 9.plasmid containing c.1210-3C together with T7 sequence produced a normal transcript and partial exon10-skipping-transcript, whereas mutant plasmid containing c.1210-3G in cis with T5 sequence causedOverall, c.1210-3C>G, the newly identified pathogenic mutation in our patient, in combination with T5

Keywords： cystic fibrosis     CFTR     splicing mutation     minigene    

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Changes of phenotype and function of human CD4 CD25 T cells induced by transfection of Foxp3

WU Kui, BI Yutian, WANG Yaoli, WANG Changzheng

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 366-369 doi: 10.1007/s11684-008-0070-6

Abstract: of naive CD4 T cells.The pMSCV-Foxp3 retroviral vector encoding Foxp3 gene was transduced into the PT67 packaging cell lineFoxp3-gene transfected CD4 T cells could express Foxp3 and transfection of Foxp3 gene up-regulated theCD4CD25 T cells acquired a regulatory phenotype and function after it was transduced with the Foxp3 geneThis suggested a key role of Foxp3 in the generation of CD4CD25 regulatory T cells.
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randomized trials of maintenance bacillus Calmette-Guerin instillation efficacy against recurrence of T1G3

PAN Jiangang, ZHOU Xing, CHEN Zhiguang, HAN Ruifa

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 259-263 doi: 10.1007/s11684-008-0049-3

Abstract: bacillus Calmette-Guerin (BCG) could reduce recurrence after transurethral resection of tumor 1 grade 3(T1G3) superficial bladder cancer.resection plus another treatment on the treatment results in patients with superficial bladder cancer of T1G3resection of bladder tumor (TURBT) is an effective conservative treatment for preventing recurrence of T1G3
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FOXP3 and Its Cofactors as Targets of Immunotherapies Review

Yasuhiro Nagai,Lian Lam,Mark I. Greene,Hongtao Zhang

Engineering 2019, Volume 5, Issue 1,   Pages 115-121 doi: 10.1016/j.eng.2019.01.001

Abstract:

Forkhead box P3 (FOXP3) is a "master regulator" of regulatory T cells (Tregs), which area subset of T cells that can suppress the antigen-specific immune reaction and that play important rolesAlthough FOXP3 per se is not an ideal drug target, deacetylases, acetyltransferases, kinases, and other enzymes that regulate the PTMs of FOXP3 are potential targets to modulate FOXP3 and TregFOXP3" side effects must be considered when inhibitors to these enzymes are used.

Keywords： Treg     Forkhead box P3 (FOXP3)     Post-translational modification     Autoimmune     Cancer    

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Ductile extension of 3-D external circumferential cracks in pipe structures

Wuchao YANG, Xudong QIAN

Frontiers of Structural and Civil Engineering 2011, Volume 5, Issue 3,   Pages 294-303 doi: 10.1007/s11709-011-0115-9

Abstract: This study investigates the ductile fracture resistance of 3-D external circumferential cracks in theThe fracture resistance along the 3-D semi-elliptical crack front is computed from the calibrated cellequivalent 2-D axi-symmetric model provides conservative estimations of the fracture resistance for 3-

Keywords： ductile fracture     computational cell method     G-T model     J-R curve    

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3D-Printed Scaffolds Promote Angiogenesis by Recruiting Antigen-Specific T Cells Article

Cuidi Li, Zhenjiang Ma, Wentao Li, Tianyang Jie, Liping Zhong, Hongfang Chen, Wenhao Wang, Jinwu Wang, Wenguo Cui, Yongxiang Zhao

Engineering 2022, Volume 17, Issue 10,   Pages 183-195 doi: 10.1016/j.eng.2021.05.018

Abstract: response after implantation is a primary determinant of the tissue-repair effects of three-dimensional (3Dmesoporous silica microrod (MSR)/polyethyleneimine (PEI)/ovalbumin (OVA) self-assembled vaccines with 3D-printed-- --> T helper 2 (Th2) cells can be recruited to promote early angiogenesis.scaffolds increased the proportion of Th2 cells in the spleen and locally recruited antigen-specific T

Keywords： 3D printing     Immune microenvironment regulating     Angiogenesis     Bone regeneration    

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An extended cell-based smoothed discrete shear gap method (XCS-FEM-DSG3) for free vibration analysis

Dang-TRUNG,T. NGUYEN-THOI

Frontiers of Structural and Civil Engineering 2015, Volume 9, Issue 4,   Pages 341-358 doi: 10.1007/s11709-015-0302-1

Abstract: A cell-based smoothed discrete shear gap method (CS-FEM-DSG3) was recently proposed and proven to beIn addition, due to using only three-node triangular elements generated automatically, the CS-FEM-DSG3The paper hence tries to extend the CS-FEM-DSG3 for free vibration analysis of cracked Reissner-Mindlinshells by integrating the original CS-FEM-DSG3 with discontinuous and crack−tip singular enrichmentmethod (XFEM) to give a so-called extended cell-based smoothed discrete shear gap method (XCS-FEM-DSG3)

Keywords： Reissner-Mindlin shell     free vibration analysis     cell-based smoothed discrete shear gap method (CS-FEM-DSG3)     extended cell-based smoothed discrete shear gap method (XCS-FEM-DSG3)     smoothed finite element methods    

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Interactions between metal ions and the biopolymer in activated sludge: quantification and effects of system pH value

Yun Zhou, Siqing Xia, Binh T. Nguyen, Min Long, Jiao Zhang, Zhiqiang Zhang

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 1, doi: 10.1007/s11783-017-0898-6

Abstract: The biopolymer showed two protein-like fluorescence peaks (peaks A and B). Interactions of Pb(II) and biopolymer were quantified at various system pH values. System pH values significantly affect the quenching constant values for both peaks. Peak B plays a more important role in the interactions than peak A. Removal mechanism of metal ions by activated sludge system was further disclosed. The quantification and effects of system pH value on the interactions between Pb(II) and the biopolymer from activated sludge were investigated. The biopolymer had two protein-like fluorescence peaks (Ex/Em= 280 nm/326–338 nm for peak A; Ex/Em= 220–230 nm/324–338 nm for peak B). The fluorescence intensities of peak B were higher than those of peak A. The fluorophores of both peaks could be largely quenched by Pb(II), and the quencher dose for peak B was about half of that for peak A. The modified Stern-Volmer equation well depicted the fluorescence quenching titration. The quenching constant (Ka) values for both peaks decreased with rising system pH value, and then sharply decreased under alkaline conditions. It could be attributed to that the alkaline conditions caused the reduction of available Pb(II) due to the occurrence of Pb(OH)2 sediments. The Ka values of peak B were bigger than those for peak A at the same system pH values. Accordingly, the aromatic protein (peak B) plays the key role in the interactions between metal ions and the biopolymer.

Keywords： Metal ions     Biopolymer     Activated sludge     Three-dimensional excitation emission matrix (3D-EEM)     Fluorescence    

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3D finite element prediction of chip flow, burr formation, and cutting forces in micro end-milling ofaluminum 6061-T6

A. DAVOUDINEJAD, P. PARENTI, M. ANNONI

Frontiers of Mechanical Engineering 2017, Volume 12, Issue 2,   Pages 203-214 doi: 10.1007/s11465-017-0421-6

Abstract: This study proposed a 3D finite element modeling (3D FEM) approach for the micro end-milling of Al6061-T6.The proposed 3D FE model considers the effects of mill helix angle and cutting edge radius on the chip

Keywords： 3D finite element modeling     micro end-milling     cutting force     chip formation     burr formation    

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Title Author Date Type Operation

Identification and ecotoxicity assessment of intermediates generated during the degradation of clofibric acid by advanced oxidation processes

Wenzhen LI, Yu DING, Qian SUI, Shuguang LU, Zhaofu QIU, Kuangfei LIN

Journal Article

spp., foodborne pathogens threatening neonates and infants

Qiming CHEN, Yang ZHU, Zhen QIN, Yongjun QIU, Liming ZHAO

Journal Article

A CASE FOR ASSESSING ALLOCASUARINA AND CASUARINA SPP.

Journal Article

Repeats in the transcribed regions: comprehensive characterization and comparison of

Manosh Kumar BISWAS, Christoph MAYER, Xiuxin DENG

Journal Article

CRISPR-Cas9 mediated LAG-3 disruption in CAR-T cells

Yongping Zhang, Xingying Zhang, Chen Cheng, Wei Mu, Xiaojuan Liu, Na Li, Xiaofei Wei, Xiang Liu, Changqing Xia, Haoyi Wang

Journal Article

Influence and related mechanism of Retn gene expression on glucose uptake in 3T3-L1 cells

LI Yahui, DONG Shiyuan, YU Chao, JIANG Yu, LI Huaixing, SUN Shuhan

Journal Article

Novel mutation c.1210-3C>G in with a poly-T tract of 5T affects mRNA splicing in a Chinese patient

Journal Article

Changes of phenotype and function of human CD4 CD25 T cells induced by transfection of Foxp3

WU Kui, BI Yutian, WANG Yaoli, WANG Changzheng

Journal Article

randomized trials of maintenance bacillus Calmette-Guerin instillation efficacy against recurrence of T1G3

PAN Jiangang, ZHOU Xing, CHEN Zhiguang, HAN Ruifa

Journal Article

FOXP3 and Its Cofactors as Targets of Immunotherapies

Yasuhiro Nagai,Lian Lam,Mark I. Greene,Hongtao Zhang

Journal Article

Ductile extension of 3-D external circumferential cracks in pipe structures

Wuchao YANG, Xudong QIAN

Journal Article

3D-Printed Scaffolds Promote Angiogenesis by Recruiting Antigen-Specific T Cells

Cuidi Li, Zhenjiang Ma, Wentao Li, Tianyang Jie, Liping Zhong, Hongfang Chen, Wenhao Wang, Jinwu Wang, Wenguo Cui, Yongxiang Zhao

Journal Article

An extended cell-based smoothed discrete shear gap method (XCS-FEM-DSG3) for free vibration analysis

Dang-TRUNG,T. NGUYEN-THOI

Journal Article

Interactions between metal ions and the biopolymer in activated sludge: quantification and effects of system pH value

Yun Zhou, Siqing Xia, Binh T. Nguyen, Min Long, Jiao Zhang, Zhiqiang Zhang

Journal Article

3D finite element prediction of chip flow, burr formation, and cutting forces in micro end-milling ofaluminum 6061-T6

A. DAVOUDINEJAD, P. PARENTI, M. ANNONI

Journal Article